Dr Declan Gaynor Research Profile

Dr Declan Gaynor

Lecturer in Chemistry and Academic Director of IT

Email: dgaynor@rcsi-mub.com

Tel: +97317351450     Ext:  2300


Biography

Declan Gaynor, BSc, MSc, PhD (NUID) completed his chemistry degree at University College Dublin (1998) before moving to RCSI to work under the supervision of Prof. Kevin B Nolan (1998 – 2002). During this time he completed his PhD in bioinorganic chemistry.  In 2002 he spent eight months in the laboratory of Prof G W Canters at Universitat Leiden, Netherlands on a Marie Curie studentship in addition to working in the laboratory of Prof W Haase in Universitat Darmstadt, Germany on a number of occasions between 1998 and 2002.  Following his PhD, he spent two years (2002-2004) as Lecturer in Chemistry at the Royal College of Surgeons in Ireland during which time he completed an MSc in Multimedia Systems at Trinity College, Dublin University (2004).  In September 2004 to present he has worked as Lecturer in Chemistry at RCSI Bahrain.  During this time he has managed a large number of administrative roles such as administrator of the virtual learning environment, webmaster of the university website, learning technology coordinator and currently academic director of IT.  Dr Gaynor currently has active collaborations with Dr Ahmed Taha and Dr Salwa Al Thawadi in the College of Sciences at the University of Bahrain, Dr Darren Griffith and Dr Celine Marmion in RCSI Dublin and Dr Leigh Jones at the Department of Chemistry in the National University of Ireland, Galway.  Apart from teaching and research, Declan is involved in many sporting activities.  He is a keen runner, wakeboarder, kitesurfer and surfski paddler.  Recently Declan founded the first surfski paddling club in Bahrain at the Amwaj Marina on the Amwaj Islands. 


Research Interests

Synthesis of hydroxamic acid analogues of aspirin as inhibitors of cyclooxygenase.

Synthesis of platinum(II) and platinum(IV) complexes as possible antitumour drugs.

Metal complexes and their antimicrobial activity.

 

Publications

1. Metal Complexes of Cyclic Hydroxamates. Synthesis and crystal structures of 3-hydroxy-2-methyl-3H-quinazolin-4-one (ChaH) and of its Fe(III), Co(II), Ni(II), Cu(II) and Zn(II) complexes, Alagha, A., Parthasarathi, L., Gaynor, D, Müller-Bunz, H., Starikova, Z. A., Farkas, E., O'Brien, E.C., Gil, M.J., Nolan, K. B., 2011, 386, 58 - 66.

2. fac-Tris(4-aminobenzohydroxamato)iron(III) ethanol solvate, Alagha A. B. M., Gaynor, D., Mueller-Bunz, H., Nolan, K. B., Parthasarathi., L., Acta Crystallographica Section E-Structure Reports Online, 2010, 66, M853-U1294

3. Synthesis and structure of a heptanuclear nickel(II) complex uniquely exhibiting four distinct binding modes, two of which are novel, for a hydroxamate ligand, D. Gaynor, Z. A. Starikova, S. Ostrovsky, W. Haase and K. B. Nolan, J. Chem. Soc., Chem. Commun., 2002, 506-507.

4. Hydroxamic acids, their metal complexes and biological applications, Gaynor, D., Starikova, Z. A., Haase, W., Nolan K. B., J. Inorg. Biochem., 2001, 86, 1, 230-230

5. Copper(II) complexes of isomeric aminophenylhydroxamic acids. A novel 'clam-like' dimeric metallacrown and polymeric helical structure containing interlinked unique copper(II) sites, D. Gaynor, Z. A. Starikova, W. Haase and K. B. Nolan, J. Chem. Soc., Dalton Trans., 2001, 1578-1581.